THE ROLE OF PLANT IN THE TREATMENT OF DISEASES CAUSED BY MICROORGANISMS BASED IN THE NATURAL PRODUCTS

THE ROLE OF PLANT IN THE TREATMENT OF DISEASES CAUSED BY MICROORGANISMS BASED IN THE NATURAL PRODUCTS   CHAPTER ONE INTRODUCTION 1.1 Background Traditional medicine is defined as the sum total of knowledge, skills, and practices based on the theories, beliefs, and experiences indigenous to different cultures that are used to maintain health, as well […]

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EVALUATION OF THE ANTIDIABETIC EFFECTS OF WATER AND METHANOLIC EXTRACTS OF AVOCADO (PERSEA AMERICANA) SEED ON ALLOXAN INDUCED DIABETIC RATS

EVALUATION OF THE ANTIDIABETIC EFFECTS OF WATER AND METHANOLIC EXTRACTS OF AVOCADO (PERSEA AMERICANA) SEED ON ALLOXAN INDUCED DIABETIC RATS     CHAPTER ONE   INTRODUCTION   BACKGROUND   During the past decade, the traditional systems have gained importance in the field of medicine. The World Health Organization estimates that 4 billion people, 80% of […]

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PHYTOCHEMICAL ANALYSIS AND THE ANTIINFLAMMATORY ACTIVITIES OF DICHLOROMETHANE FRACTION OF METHHANOL EXTRACT OF CRATEVA ADANSONII

PHYTOCHEMICAL ANALYSIS AND THE ANTIINFLAMMATORY ACTIVITIES OF DICHLOROMETHANE FRACTION OF METHHANOL EXTRACT OF CRATEVA ADANSONII ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 […]

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PHYTOCHEMICAL ANALYSIS AND THE ANTIINFLAMMATORY ACTIVITIES OF DICHLOROMETHANE FRACTION OF METHHANOL EXTRACT OF CRATEVA ADANSONII

PHYTOCHEMICAL ANALYSIS AND THE ANTIINFLAMMATORY ACTIVITIES OF DICHLOROMETHANE FRACTION OF METHHANOL EXTRACT OF CRATEVA ADANSONII ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 […]

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DETERMINATION OF PRION PROTEIN (PrP) AND CHANGES IN FERTILITY HORMONES WITH SLEEP DEPRIVATION IN ALBINO RATS

DETERMINATION OF PRION PROTEIN (PrP) AND CHANGES IN FERTILITY HORMONES WITH SLEEP DEPRIVATION IN ALBINO RATS ABSTRACT Wistar albino rats, numbering thirty five (35), were nurtured in the animal house of University of Nigeria Enugu Campus and used for this work. This work is designed to determine the presence of prion (PrP) in Wistar albino […]

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EFFECTS OF ALCOHOL ON SOME BIOCHEMICAL PARAMETERS OF ALCOHOLICS

EFFECTS OF ALCOHOL ON SOME BIOCHEMICAL PARAMETERS OF ALCOHOLICS   ABSTRACT This work was aimed at finding the effects of alcohol on some biochemical parameters. A total of one hundred and eighty (180) apparently healthy, non-hypertensive male alcoholics were used for the study. Forty (40) non-consumers of alcohol were used as control. The activity of […]

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EFFECTS OF ETHANOL, METHANOL AND N-HEXANE LEAF AND FRUIT EXTRACTS OF Kigelia africana ON SOME OXIDATIVE AND BIOCHEMICAL PARAMETERS IN ALLOXAN-INDUCED DIABETIC RATS

EFFECTS OF ETHANOL, METHANOL AND N-HEXANE LEAF AND FRUIT EXTRACTS OF Kigelia africana ON SOME OXIDATIVE AND BIOCHEMICAL PARAMETERS IN ALLOXAN-INDUCED DIABETIC RATS   ABSTRACT Globally, the estimated incidence of diabetes and projection for the year 2030 as given by the International Diabetes Federation (IDF) is 350 million. Kigelia africana is highly used for ethnomedicinal […]

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ELUCIDATION OF SOME IMMUNOLOGICAL AND BIOCHEMICAL NATURE OF THE LEAVES OF SENNA MIMOSOIDES

ELUCIDATION OF SOME IMMUNOLOGICAL AND BIOCHEMICAL NATURE OF THE LEAVES OF SENNA MIMOSOIDES   ABSTRACT In the present study, the phytochemical composition, immunomodulatory, leukocyte mobilization, haematological and antihepatotoxic effects of the aqueous extract of Senna mimosoides leaves were evaluated. The study also covered the effect of the extract on theactivity of lactase and the assessment of the damaging […]

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MODULATION OF IMMUNOLOGICAL RESPONSES IN ALBINO RATS BY LEAF EXTRACTS OF TELFAIRIA OCCIDENTALIS (HOOK F) AND TECTONA GRANDIS (LINN)

MODULATION OF IMMUNOLOGICAL RESPONSES IN ALBINO RATS BY LEAF EXTRACTS OF TELFAIRIA OCCIDENTALIS (HOOK F) AND TECTONA GRANDIS (LINN)   ABSTRACT The immuno-modulating effects of leaf extracts of Telfairia occidentalis (Hook F) and Tectona grandis (Linn) on both humoral and cell mediated immune responses were evaluated in vivo.The responding cells were defined by flow cytometry and secretion of various cytokines by […]

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NUTRITIONAL POTENTIAL OF SYNSEPALUM DULCIFICUM PULP AND THE EFFECT OF THE METHANOLIC EXTRACT ON SOME BIOCHEMICAL PARAMETERS IN ALBINO RATS

NUTRITIONAL POTENTIAL OF SYNSEPALUM DULCIFICUM PULP AND THE EFFECT OF THE METHANOLIC EXTRACT ON SOME BIOCHEMICAL PARAMETERS IN ALBINO RATS ABSTRACT The nutritive and antinutritive compositions of S. dulcificum pulp were analysed to augment the available information on the anti-diabetic effect of the plant. Biochemical parameters like liver function enzymes (ALT, AST, ALP) and bilirubin concentrations,serum total […]

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BIOCHEMICAL CHANGES ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA (BPH) IN AGEING MEN ATTENDING CLINIC

BIOCHEMICAL CHANGES ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA (BPH) IN AGEING MEN ATTENDING CLINIC   ABSTRACT This study was aimed at investigating biochemical changes associated with benign prostatic hyperplasia in ageing men attending clinic at the university of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria. The assessment included 50 men with BPH attending clinic in addition […]

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COMPARATIVE STUDIES OF THE SUGAR AND MINERAL CONTENTS OF INDUSTRIALLY PROCESSED FRUIT JUICES SOLD WITH FRESHLY PREPARED FRUIT JUICES

COMPARATIVE STUDIES OF THE SUGAR AND MINERAL CONTENTS OF INDUSTRIALLY PROCESSED FRUIT JUICES SOLD WITH FRESHLY PREPARED FRUIT JUICES ABSTRACT The sugar and mineral levels of industrially processed fruit juices (mainly 100% and 50% fruit juices) sold to consumers in Enugu state, Nigeria were determined and compared with that of freshly prepared fruit juices. The […]

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EFFECT OF CONTROLLED FERMENTATION USING ASPERGILLUS NIGER AND TRICHODERMA HARZANIUM ON NUTRIENT COMPOSITION OF PRE-TREATED BENGAL INDIGO (INDIGOFERA ARRECTA) SEEDS

EFFECT OF CONTROLLED FERMENTATION USING ASPERGILLUS NIGER AND TRICHODERMA HARZANIUM ON NUTRIENT COMPOSITION OF PRE-TREATED BENGAL INDIGO (INDIGOFERA ARRECTA) SEEDS   CHAPTER 1 INTRODUCTION The genus Indigofera Linn. is a large genus of about 700 species of flowering plants belonging to the sub-family Papilionoideae in the family Fabaceae / Leguminosae. They occur throughout the tropical and subtropical […]

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EVALUATION OF THYROID DYSFUNCTION IN TYPE 2 DIABETIC PATIENT

EVALUATION OF THYROID DYSFUNCTION IN TYPE 2 DIABETIC PATIENT ABSTRACT Diabetes Mellitus (DM) and Thyroid Dysfunction (TD) are the two most common endocrinopathies seen in general population. Type 2 diabetes mellitus(T2DM) is commonly associated with altered thyroid function. The aim of the research is to evaluate TD in patients with T2DM attending Endocrinology Clinic of […]

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STUDY ON THE DESTABILIZATION OF LYSOZYME AND THE CHAPERONE-LIKE ACTIVITY OF ALPHA CRYSTALLIN

STUDY ON THE DESTABILIZATION OF LYSOZYME AND THE CHAPERONE-LIKE ACTIVITY OF ALPHA CRYSTALLIN ABSTRACT Destabilization of Lysozyme and chaperone like action of alpha crystallin isolated from goat’s eye lens was investigated at various temperature ranges in phosphate buffer (pH 7.1) solution and dithiothretol (DTT). This was monitored spectrophotometrically at 260nm. The heat and DTT-induced destabilization […]

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ASSESSMENT OF DIETARY PATTERN AND NUTRITIONAL STATUS OF PEOPLE LIVING WITH HIV/AIDS ATTENDING SOME VOLUNTARY AND COUNSELLING TEST (VCT) UNITS

ASSESSMENT OF DIETARY PATTERN AND NUTRITIONAL STATUS OF PEOPLE LIVING WITH HIV/AIDS ATTENDING SOME VOLUNTARY AND COUNSELLING TEST (VCT) UNITS   ABSTRACT This study assessed the dietary pattern and nutritional status of People Living with HIV/AIDS (PLWHA) attending some voluntary and counseling test units in Kaduna metropolis.The studied subjects consisted of 74 adult patients infected […]

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ASSESSMENT OF THE RELATIONSHIP BETWEEN SOME TRACE ELEMENTS AND ANTIOXIDANT ENZYMES IN UNDER-FIVE CHILDREN WITH PROTEIN- ENERGY MALNUTRITION

ASSESSMENT OF THE RELATIONSHIP BETWEEN SOME TRACE ELEMENTS AND ANTIOXIDANT ENZYMES IN UNDER-FIVE CHILDREN WITH PROTEIN- ENERGY MALNUTRITION ABSTRACT Assessment of the relationship between some trace elements and antioxidant enzymes was carried out on 98 under-five children with protein-energy malnutrition (PEM) and 98 age- and sex-matched apparently healthy children (control). The malnourished children involve those […]

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CHARACTERIZATION, INSECTICIDAL AND MOSQUITO REPELLENCY PROPERTIES OF ESSENTIAL OILS FROM HYPTIS SUAVEOLENS LEAVES

CHARACTERIZATION, INSECTICIDAL AND MOSQUITO REPELLENCY PROPERTIES OF ESSENTIAL OILS FROM HYPTIS SUAVEOLENS LEAVES   ABSTRACT Essential oils were extracted from the leaves of Hyptis suaveolens by hydro-distillation, Mosquitocidal effect was done through an experiment devised for the purpose of this research. The effect of the essential oils against mosquito larvae (larvicidal), mosquito repellency effect and physicochemical properties […]

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ISOLATION, PURIFICATION AND CHARACTERIZATION OF FREE AND IMMOBILIZED ALPHA-AMYLASE FROM BACILLUS LICHENIFORMIS

ISOLATION, PURIFICATION AND CHARACTERIZATION OF FREE AND IMMOBILIZED ALPHA-AMYLASE FROM BACILLUS LICHENIFORMIS   ABSTRACT The bacteria Bacillus licheniformis was cultured in nutrient agar and then incubated for 15h at 35oC. The bacteria cells were harvested by centrifugation after incubation. The cell free supernatant was used to estimate alpha-amylase activity. The alpha-amylase obtained was isolated and purified using ammonium sulfate precipitation, gel […]

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LARVICIDAL POTENTIAL OF EXTRACTS OF Persea Americana SEED AND Chromolaena odorata LEAF AGAINST Aedes vittatus MOSQUITO

LARVICIDAL POTENTIAL OF EXTRACTS OF Persea Americana SEED AND Chromolaena odorata LEAF AGAINST Aedes vittatus MOSQUITO   ABSTRACT The larvicidal activity of various solvent (ethanol, ethyl acetate and n-hexane) extracts of Persea americana seed and Chromolaena odorata leaves against Aedes vittatus mosquitowas analysed. The most potent solvent (n-hexane) extracts of both plants were fractionated using column chromatography and most effective […]

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A PROJECT RESEARCH INTO SERUM CALCIUM LEVEL IN GERIATRIC MEN, COMPERATIVE STUDIES

A PROJECT RESEARCH INTO SERUM CALCIUM LEVEL IN GERIATRIC MEN, COMPERATIVE STUDIES   ABSTRACT Calcium is the most important mineral in the body. The body needs calcium for normal functioning of nerves and muscles including the most important muscles of all which is the heart. Calcium is also important for healthy bones and teeth. The […]

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PACKED BED REACTOR SYSTEM STUDY ON THE BIOSORPTION OF Cr(VI) FROM AQUEOUS SOLUTION USING CORN COB POWDER

PACKED BED REACTOR SYSTEM STUDY ON THE BIOSORPTION OF Cr(VI) FROM AQUEOUS SOLUTION USING CORN COB POWDER ABSTRACT The current method used in the treatment of Cr(VI) uses biosorbents that are expensive hence the need for cheaper available biosorbent. In this study,potential use of corn cob powder biomass, as a bioremediation agent for the removal […]

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CARDIO PROTECTIVE ACTIVITIES OF N-HEXANE EXTRACT OF DESMODIUM VELUTINUM STEM ON ALBINO WISTER RAT

CARDIO PROTECTIVE ACTIVITIES OF N-HEXANE EXTRACT OF DESMODIUM VELUTINUM STEM ON ALBINO WISTER RAT ABTRACT This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four […]

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ANTILIPIDEMIC EFFECT OF WATER (H2O) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS

ANTILIPIDEMIC EFFECT OF WATER (H2O) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS   ABSTRACT This study evaluated the antilipidemic activity of water extracts from leaves of Desmodium velutinum on albino wistar rats. The phytochemical analysis of the leaf extract showed the presence of tannins, saponins, alkaloids, soluble carbohydrates, flavonoids, reducing sugar, steroids, cyanide […]

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